Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com

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Τετάρτη, 15 Αυγούστου 2018

Coexistence of medullary thyroid carcinoma and recurrent non-functional pituitary adenoma: a case report

Medullary thyroid carcinoma and pituitary adenoma are neuroendocrine tumors and their coexistence has not been reported in the literature, previously. Medullary thyroid carcinoma is a neoplasm of the thyroid g...

https://ift.tt/2w9DcUH

Ecological risk assessment of potentially toxic elements (PTEs) in the soil-plant system after reclamation of dredged sediment

Abstract

The Shayinghe River is an important tributary of the Huaihe River in China. The concentrations of potential toxic elements (PTEs), such as As, Hg, Pb, Cu, Zn, Cr, and Cd in soils and dominant vegetation from mud-dumping areas reclaimed with dredged sediments, and areas without mud-dumping (non-mud-dumping areas) adjacent to the Shayinghe River were investigated. The potential ecological risk index (ERI) and transfer coefficient (TC) were calculated and evaluated. The results showed that the potential toxic element concentrations in all sampling areas decreased in the order of (Zn, Cr) > (Cu, Pb) > As>Cd > Hg. Additionally, the total concentrations of the PTEs significantly increased from mud-dumping to the non-mud-dumping areas. Ecological risk assessment of soils showed that all the elements did not exhibit apparent ecological risks (except for As). This element exhibited a moderate ecological risk, implying that the dredging of sediments could increase the potential ecological risk of individual PTEs. Additionally, the PTEs in some of dominant plants in mud-dumping areas did not increase, indicating no apparent accumulation. The principal component analysis (PCA) showed that the principal components of the PTEs in plants from dredged sediments were different from those in the agricultural soil, indicating the influence of dredging on PTEs. Finally, Cd, Zn, and Hg had higher transfer coefficients (up to 6), even if their concentrations were relatively low, suggesting potential ecological risks to the plants.



https://ift.tt/2vOnBKF

Research on the ecological efficiency of the Yangtze River Delta region in China from the perspective of sustainable development of the economy-energy-environment (3E) system

Abstract

Balancing the relationship between economic development, energy utilization, and environmental protection has become an important task in China's Strip Planning and Construction. This article takes the annual panel data from 2005 to 2015 as the research object firmly grasps the research basis of the Economy-Energy-Environment (3E) System, and focuses on building a new research framework from both internal and external perspectives of the eco-efficiency index to achieve the exploratory research on regional ecological efficiency changes and influencing factors. First of all, it uses super-efficient slacks-based measure (SBM) model which introduces undesired outputs to measure eco-efficiency at different levels. Then, it applies Malmquist index to calculate total factor productivity and structural efficiencies. Finally, it selects six indicators and uses the STIRPAT regression model to analyze external factors. The results indicate that (1) the overall ecological efficiency is effective and maintaining a good momentum of development. Among all the cities and provinces, Shanghai and Zhejiang provinces play the role of "stabilizers," while Jiangsu and Anhui provinces act as "accelerators." (2) All 41 prefecture-level cities can be divided into four different types, i.e., "high-high", "low-high", "low-low," and "high-low" cities, and there is an obvious phenomenon of spatial clustering; (3) pure technical efficiency and scale efficiency is the core driving force for the improvement of ecological efficiency. (4) Anhui and Jiangsu provinces show a U-shaped relationship, while Zhejiang province shows an inverted U-shaped relationship.

Graphical abstract

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https://ift.tt/2Blo5Nw

Mesenchymal Stem Cells and Stromal Vascular Fraction for Hair Loss

The current state of the applicability of cell therapy for the treatment of various conditions of hair loss reveals a promising and potentially effective role. Further research, based on published work to date, is indicated to further explore the potential roles of autologous fat grafting, mesenchymal stem cells, and stromal vascular fraction therapy. The authors' evolving experience matches these promising scientific findings.

https://ift.tt/2nDNF6K

Microneedling with Biologicals

Microneedling is a popular and cost-effective treatment with little down time. The application of topical agents to enhance outcomes is common practice. Microchannels created with nonthermal needling close at 4 hours to 6 hours due to fibrin plugs. Channels created with thermal needling or fractional laser stay open longer and enhance drug or biological uptake more due to the dermal sponge injury pattern that is created. Nonthermal microneedling devices may need Food and Drug Administration clearance, which also notes that dermaceuticals should be considered drugs in many cases.

https://ift.tt/2MSx7mv

Mesothelial Stem Cells and Stromal Vascular Fraction

Autologous human fat-derived mesenchymal stem cells are present in stromal vascular fraction. Stromal vascular fraction can be easily and safely extracted from lipoaspirate. The regenerative, antiinflammatory and immunomodulatory effects of stromal vascular fraction are being documented in ongoing therapeutic response studies.

https://ift.tt/2PditIf

Introduction

The use of biologicals for clinical use is rapidly increasing. One of the logical questions is what constitutes a biological? The official definition of biological products by the Food and Drug Administration is "Biological products can be composed of sugars, proteins, or nucleic acids, or a combination of these substances. They may also be living entities, such as cells and tissues. Biologics are made from a variety of natural resources—human, animal, and microorganism—and may be produced by biotechnology methods."

https://ift.tt/2MMwhaX