Evaluation of Clinical Significance of Lymphovascular Space Invasion in Stage IA Endometrial Cancer

alwin shared this article with you from Inoreader Evaluation of Clinical Significance of Lymphovascular Space Invasion in Stage IA Endometrial Cancer Via Oncology Conclusion: LVSI was not a prognostic factor of not only stage IA endometrial cancer, but also stage IA low-grade cancer. (Source: Oncology) View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Evaluation of Clinical Significance of Lymphovascular Space Invasion in Stage IA Endometrial Cancer

alwin shared this article with you from Inoreader Evaluation of Clinical Significance of Lymphovascular Space Invasion in Stage IA Endometrial Cancer Via Oncology CONCLUSION: LVSI was not a prognostic factor of not only stage IA endometrial cancer, but also stage IA low-grade cancer.PMID:34915516 | DOI:10.1159/000521382 (Source: Oncology) View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Life and death of microglia: mechanisms governing microglial states and fates

alwin shared this article with you from Inoreader Life and death of microglia: mechanisms governing microglial states and fates Via Immunology Letters Immunol Lett. 2022 Apr 9:S0165-2478(22)00042-6. doi: 10.1016/j.imlet.2022.04.001. Online ahead of print.ABSTRACTRecent advances in genetic analysis and intensive research have revealed that microglial cells respond to external stimuli in various ways and adopt diverse states. Herein, we summarize the current knowledge on the possible microglial states during development, homeostasis, and perturbation. These states are characterized either by irreversible cellular changes, such as cell death and cellular senescence, or reversible alterations, triggered by temporary changes in the microenvironment. Subsequently, we discuss the modalities of the transcriptional and functional recovery of microglia from a molecular perspective. An understanding of (ir)reversible changes in their cellular fates... View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Using Classical Test Theory to Determine the Psychometric Properties of the Deglutition Handicap Index

alwin shared this article with you from Inoreader Using Classical Test Theory to Determine the Psychometric Properties of the Deglutition Handicap Index Via Dysphagia AbstractThe Deglutition Handicap Index (DHI) is a self-report measure for patients at risk of oropharyngeal dysphagia on deglutition-related aspects of functional health status (FHS) and health-related quality of life (HR-QoL). The DHI consists of 30 items which are subsumed within the Symptom, Functional and Emotional subscales. The purpose of this study was to evaluate the psychometric properties of the DHI using Classic Test Theory according to the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) criteria. A total of 453 patients with dysphagia with different aetiologies were recruited concurrently at two academic hospitals. Dysphagia was confirmed by fiberoptic endoscopic and/or videofluoroscopic evaluation of swallowing. In addition, a healthy con... View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Investigation of the Effect of Radiotherapy Dose on Chewing and Swallowing Structures in Head and Neck Cancer Patients Treated with Concomitant Chemoradiotherapy

alwin shared this article with you from Inoreader Investigation of the Effect of Radiotherapy Dose on Chewing and Swallowing Structures in Head and Neck Cancer Patients Treated with Concomitant Chemoradiotherapy Via Dysphagia AbstractIntensity-modulated radiotherapy (IMRT) is a treatment method that is used in the treatment of head and neck cancers. Impairment of chewing and swallowing functions in the early and late periods of radiotherapy is frequent. Therefore, revealing the dose –effect relationship is important. The main purpose of this study is to investigate the dose–effect relationship between chewing and swallowing structures objectively via a standardized videofluoroscopy protocol. The study included 35 participants treated with chemo-IMRT. A videofluoroscopic swa llowing study (VFSS) was performed before IMRT, and 3 and 6 months after IMRT. VFSS results were scored according to the Modified Barium Swallow Impairment Profile (MBSImP) and the Penetration-Aspiration Scale (PAS). Maximum interinciso... View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

A Novel Balloon Catheter-based Dilation Intervention for Patients with Cricopharyngeus Achalasia After Stroke: A Randomized Study

alwin shared this article with you from Inoreader A Novel Balloon Catheter-based Dilation Intervention for Patients with Cricopharyngeus Achalasia After Stroke: A Randomized Study Via Dysphagia This study aimed to investigate the efficacy and safety of a novel balloon catheter in dilation intervention for patients with cricopharyngeus achalasia after stroke. Thirty-four patients with cricopharyngeus achalasia after stroke received routine swallowing rehabilitation training and were randomly assigned to an experimental group (Exp,n = 17) that received dilation therapy using the novel balloon catheter once daily for 5 days per week or a control group (Con,n = 17) that received dilation therapy with a 14-Fr ordinary urinary catheter once daily for 5 days per week. The intervention duration, Eating Assessment Tool (EAT)-10 scores, and Functional Oral Intake Scale (FOIS) scores were recorded at baseline and each day during intervention. The time for a patient's FOIS score ... View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Mortality from Aspiration Pneumonia: Incidence, Trends, and Risk Factors

alwin shared this article with you from Inoreader Mortality from Aspiration Pneumonia: Incidence, Trends, and Risk Factors Via Dysphagia AbstractAspiration pneumonia is a potentially preventable, aggressive type of pneumonia. Little is understood on the burden in mortality from aspiration pneumonia. Our objectives were to first examine the burden of mortality from aspiration pneumonia in the United States and second investigate comorbidities associated with aspiration pneumonia to understand risk factors. We conducted a case –control study of individuals who died of aspiration pneumonia matched to those who died of other causes. We analyzed all deaths in the United States using the Multiple Cause of Death Dataset from 1999 to 2017. Cases were matched with controls based on age, sex, and race. We calculated age-adjuste d mortality rates, annual percentage changes in aspiration pneumonia mortality, and matched odds ratio co... View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

New Radioprotective Device that can be Used for Fluoroscopic Exam: Possibility to Contribute to Staff Exposure Protection During VFSS

alwin shared this article with you from Inoreader New Radioprotective Device that can be Used for Fluoroscopic Exam: Possibility to Contribute to Staff Exposure Protection During VFSS Via Dysphagia AbstractThe videofluoroscopic swallowing study (VFSS) is a recognized standard diagnostic imaging technique that is used to investigate swallowing disorders and dysphagia. Patients were assessed in a seated posture on a chair or wheelchair. Using X-ray fluoroscopy, the state of patients ' swallowing was checked by eating and drinking according to the physician's instructions. VFSS procedures are prolonged, and VFSS staff members are exposed to radiation. Therefore, we evaluated original lead shielding device (OLSD) that can be attached to the handrail of a table and placed vertic ally. The OLSD has a lead-equivalent thickness of 0.3 mmPb, weighs about 6 kg, and has the dimensions 50 cm × 50 cm × 8.0 mm. We used a human phantom and a radiation survey meter with and without p... View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Expiratory Muscle Strength Training for Drooling in Adults with Parkinson ’s Disease

alwin shared this article with you from Inoreader Expiratory Muscle Strength Training for Drooling in Adults with Parkinson 's Disease Via Dysphagia This study explored the effect of an alter native therapy approach for drooling that aimed at improving the swallow, expiratory muscle strength training (EMST). Sixteen participants received EMST over a 6- to 8-week period. Measurements were taken pre- and post-training for drooling (Sialorrhea Clinical Scale for Parkinson's Disease; SCS-P D), swallowing, lip strength and peak cough flow. Measures of drooling, swallowing and peak cough flow were stable over pre-training assessments and improved following training (p  <  0.01). The most conservative estimate of the within-group change for SCS-PD was − 2.50 (95% confidence interval −  3.22 to −  1.22). No adverse effects were reported and participants gave high satisfaction ratings for the training. A programme of EMST ... View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Effect of Intensive Oropharyngeal Training on Radiotherapy-Related Dysphagia in Nasopharyngeal Carcinoma Patients

alwin shared this article with you from Inoreader Effect of Intensive Oropharyngeal Training on Radiotherapy-Related Dysphagia in Nasopharyngeal Carcinoma Patients Via Dysphagia ConclusionsThis study indicated that intensive oropharyngeal training improves swallowing function after radiotherapy in patients with nasopharyngeal carcinoma. (Source: Dysphagia) View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Translating Ultrasound into Clinical Practice for the Assessment of Swallowing and Laryngeal Function: A Speech and Language Pathology-Led Consensus Study

alwin shared this article with you from Inoreader Translating Ultrasound into Clinical Practice for the Assessment of Swallowing and Laryngeal Function: A Speech and Language Pathology-Led Consensus Study Via Dysphagia This study aimed to establish consensus on the priorities for translation of US into clinical practice for the assessment of swallowing and laryngeal function. Nominal Group Technique (NGT) was used as a formal method of consensus development. Clinicians and academics, all members of an international US working group, were invited to participate in the study. Two NGT meetings were held, where participants silently generated and then shared ideas. Participants anonymously ranked items. Rankings were aggregated before participants re-ranked items in order of priority. Discussions regarding rankings were recorded and transcribed to inform analysis. Member-checking with participants informed the final analysis. Participants (n = 15) were speech and language pathologists, physiotherapists a... View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Identifying Dysphagia and Demographic Associations in Older Adults Using Electronic Health Records: A National Longitudinal Observational Study in Wales (United Kingdom) 2008 –2018

alwin shared this article with you from Inoreader Identifying Dysphagia and Demographic Associations in Older Adults Using Electronic Health Records: A National Longitudinal Observational Study in Wales (United Kingdom) 2008 –2018 Via Dysphagia This study has confirmed the association of dysphagia with increasing age and frailty. A previously unreported association wit h deprivation has been identified. Deprivation is a multifactorial problem that is known to affect health outcomes, and the association with dysphagia should not be a surprise. Research in to this relationship is indicated. (Source: Dysphagia) View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Prevalence and Risk Factors of Dysphagia in Patients with Multiple Sclerosis

alwin shared this article with you from Inoreader Prevalence and Risk Factors of Dysphagia in Patients with Multiple Sclerosis Via Dysphagia AbstractDysphagia is one of the most common symptoms in multiple sclerosis (MS) patients. It can reduce the quality of life and increase the risk of mortality by developing complications such as aspiration pneumonia. The present study was conducted to estimate the prevalence of dysphagia in MS patients and investigate the associations between dysphagia and disease characteristics. The Persian version of the DYMUS questionnaire was used to assess dysphagia in 865 patients with MS, including 738 (85.3%) relapsing –remitting MS (RRMS), 106 (12.3%) secondary progressive MS (SPMS), and 21 (2.4%) primary progressive MS (PPMS). Also, demographic and clinical data, including age, sex, smoking status, Expanded Disability Status Scale (EDSS) score, disease duration, disease-modifying therapies exp... View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.