Hyperbilirubinemia and Leukocytosis in Gangrenous Cholecystitis

After reading the article "Risk factors for acute gangrenous cholecystitis in emergency general surgery patients" by Bourikian et al,1 I found it surprising that leukocytosis was not a predictor of gangrenous cholecystitis. Hyperbilirubinemia and leukocytosis continue to be important predictors of gangrenous cholecystitis.

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