GSE30341 Transcriptional analysis of ypeIR mutation in Yersinia pestis at 37°C

Contributors : Chris Minion ; Jing Yu
Series Type : Expression profiling by array
Organism : Yersinia pestis

The etiologic agent of bubonic plague, Yersinia pestis, senses cell density-dependent chemical signals to synchronize transcription between cells of the population in a process named quorum sensing. Though the closely related enteric pathogen Y. pseudotuberculosis uses quorum sensing system to regulate motility, the role of YpeIR quorum sensing in Y. pestis has been unclear. YpeIR is one of the AHL quorum sensing system in Y. pestis. In this study we performed transcriptional profiling experiments to identify Y. pestis YpeIR quorum sensing regulated functions at 37°C.

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