Fulminant corticobasal degeneration: Agrypnia excitata in corticobasal syndrome

Corticobasal degeneration (CBD) may be expressed as an atypical parkinsonism with a mean disease survival of about 7 years,1 the shortest reported survival being 24 months.2 We report a patient with corticobasal syndrome (CBS) and pathology-confirmed CBD whose 10-month course was manifested as a frontal alien hand evolving into agrypnia excitata.

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