Protection from septic peritonitis by rapid neutrophil recruitment through omental high endothelial venules

Article

Neutrophils are critical in preventing the transition of acute peritoneal infection to sepsis. Here the authors show in three mouse models of peritonitis that neutrophils enter the abdominal cavity via high endothelial venules of the greater omentum, and characterize adhesion molecules involved.

Nature Communications doi: 10.1038/ncomms10828

Authors: Konrad Buscher, Huiyu Wang, Xueli Zhang, Paul Striewski, Benedikt Wirth, Gurpanna Saggu, Stefan Lütke-Enking, Tanya N. Mayadas, Klaus Ley, Lydia Sorokin, Jian Song

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