There are limited data about outcomes after aortic valve replacement (AVR) in patients with mixed aortic valve disease (MAVD) (1). We conducted a retrospective review of all adults with moderate-to-severe MAVD who underwent AVR at Mayo Clinic from January 1, 1994 to December 31, 2014 to determine the occurrence of cardiovascular adverse events (CAE). Moderate-to-severe MAVD was defined as the combination of greater than or moderate aortic stenosis and greater than or moderate aortic regurgitation.
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