In Vivo Imaging Reveals Significant Tumor Vascular Dysfunction and Increased Tumor Hypoxia-Inducible Factor-1α Expression Induced by High Single-Dose Irradiation in a Pancreatic Tumor Model

International Journal of Radiation Oncology, Biology, Physics, Volume 97, Issue 1, 2017 Jan 1 | Maeda, Azusa, PhD; Chen, Yonghong, MSc, MD; Bu, Jiachuan, MSc;...
Summary In vivo imaging methods were used to investigate the effects of high-dose irradiation on tumor vasculature and microenvironment using a BxPC3 pancreatic tumor model. A single dose of 24 Gy caused transient vascular dysfunction associated w...

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