Is There a Prevention Effect of Fludrocortisone on Vasovagal Syncope?

We read with great interest the paper by Sheldon et al. (1) in a recent issue of the Journal. Although this research did not meet its primary objective of demonstrating that fludrocortisone reduced the likelihood of vasovagal syncope by the specified risk reduction of 40%, this study indicated a prevention effect of fludrocortisone for vasovagal syncope.

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