A case of pediatric multiple sclerosis presenting with a tumefactive demyelinating lesion.

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A case of pediatric multiple sclerosis presenting with a tumefactive demyelinating lesion.

Rinsho Shinkeigaku. 2017 Jan 28;:

Authors: Majima H, Ito T, Koyama N

Abstract
Pediatric multiple sclerosis accompanied by a tumefactive demyelinating lesion (TDL) is extremely rare. Because it is very difficult to distinguish TDLs from neoplasms, invasive brain biopsies are required for a definitive diagnosis. MR spectroscopy (MRS) without brain biopsy was recently shown diagnostic in some patients with TDLs, based on the elevation of glutamate/glutamine peaks. This report describes the clinical course of a 9-year-old girl with multiple sclerosis following a TDL and discusses the usefulness of MRS and brain biopsies to diagnose TDLs.

PMID: 28132974 [PubMed - as supplied by publisher]

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