Chronic urticaria and angioedema are skin diseases marked by the daily or almost daily occurrence of urticaria and/or angioedema for longer than 6 weeks. Although drug, food, aeroallergen, contact allergen, thyroid autoimmunity, and vitamin D associations and autoantibodies to the high affinity immunoglobulin E (IgE) receptor or free IgE might be discovered, in most cases the etiology remains idiopathic.1,2 Women represent most cases of chronic urticaria.
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