Lymph node characteristics for predicting locoregional recurrence of papillary thyroid cancer in adolescents and young adults

The biology of malignant diseases in adolescents and young adults (AYAs) between the ages of 15 and 39years is different than in younger and older persons [1]. Thyroid cancer is the fifth most common cancer in AYAs, and its incidence is rapidly increasing worldwide [1,2]. Papillary thyroid cancer (PTC) accounts for >90% of all cases [3]. The prognosis is generally excellent with appropriate therapy [4]. Compared with older adult patients, the AYA age group often presents with more advanced disease and a higher prevalence of nodal metastases [5].

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