Recurrent angioedema associated with pharmacological inhibition of dipeptidyl peptidase IV.

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Recurrent angioedema associated with pharmacological inhibition of dipeptidyl peptidase IV.

BMJ Case Rep. 2017 Jan 10;2017:

Authors: Hermanrud T, Bygum A, Rasmussen ER

Abstract
Angioedema (AE) of the upper airways is a severe and potentially life-threatening condition. The incidence has been increasing in the past two decades, primarily due to increased use of medications inhibiting the degradation of vasoactive peptides. Acquired angioedema related to angiotensin-converting enzyme inhibitors (ACEI-AAE) is well known, but other pharmaceutical agents also affect the degradation of bradykinin and substance P. We present a middle-aged man with recurrent episodes of severe AE of the oral cavity, hypopharynx and larynx due to pharmacological inhibition of dipeptidyl peptidase IV.

PMID: 28073873 [PubMed - in process]

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