Novel Immunotherapies for B-Cell Lymphomas and Leukemias.

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Novel Immunotherapies for B-Cell Lymphomas and Leukemias.

Am J Ther. 2016 Sep-Oct;23(5):e1157-81

Authors: Tees MT, Sokol L

Abstract
Current immunotherapeutic agents under investigation have the potential to significantly expand our ability to effectively treat B-cell malignancies. New disease targets, novel strategies to deliver therapy, and advanced agents that work to manipulate the immune system are a few of the ways immunotherapy has quickly evolved. Novel targeted and immune-modifying therapies may demonstrate early potential but unique toxicities and other limitations, such as difficulties in administration, must also be acknowledged. This review provides a comprehensive assessment of the current immunotherapies under investigation against B-cell malignancies.

PMID: 25237982 [PubMed - indexed for MEDLINE]

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