Polyglycolic acid sheet attached with fibrin glue can facilitate faster epithelialization of the mastoid cavity after canal wall-down tympanoplasty.

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Polyglycolic acid sheet attached with fibrin glue can facilitate faster epithelialization of the mastoid cavity after canal wall-down tympanoplasty.

Auris Nasus Larynx. 2017 Feb 16;:

Authors: Kobayashi T, Gyo K, Komori M, Hyodo M

Abstract
OBJECTIVE: This study retrospectively investigated whether polyglycolic acid (PGA) sheet attached to the bone surface using fibrin glue facilitate faster epithelialization of the mastoid bowl after canal wall-down (CWD) tympanoplasty compared to a simple dressing using poly-N-acetyl-glucosamine (Kichin) sheet.
MATERIALS AND METHODS: After completion of the CWD tympanoplasty, PGA sheet (n=16, PGA group) with fibrin glue or Kichin sheet (n=38, Kichin group) were placed on the bone surface of the mastoid bowl.
RESULTS: Postoperative epithelialization of the mastoid cavity was significantly (p<0.05) faster in the PGA group than in the Kichin group (mean 135 versus 244 days, respectively). Use of the Kaplan-Meier method showed that only the short-term epithelialization rate (up to 100 days after operation) was significantly higher. No major adverse effects related to either procedure were seen.
CONCLUSION: Epithelialization of the mastoid bowl after CWD tympanoplasty was faster in the postoperative short term when it was dressed with PGA sheet using fibrin glue compared with Kichin sheet.

PMID: 28215637 [PubMed - as supplied by publisher]

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