Are intratympanic corticosteroids effective for Ménière’s disease?

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Are intratympanic corticosteroids effective for Ménières disease?

Medwave. 2017 Mar 13;17(Suppl1):e6863

Authors: Chuang-Chuang Á, Baeza MA

Abstract
Ménières disease affects the inner ear and its main symptoms are vertigo, hearing loss and fluctuating aural symptoms. Nowadays, there are many therapeutic alternatives, being the use of intratympanic corticosteroids one that has become popular. To answer this question, we searched in Epistemonikos database, which is maintained by screening multiple databases. We identified four systematic reviews including 15 studies overall, of which seven were randomized trials. We extracted data and generated a summary of findings table using the GRADE approach. We concluded intratympanic corticosteroids probably do not decrease tinnitus, and might not decrease vertigo, hearing loss or aural fullness sensation in Ménières disease. Intratympanic corticosteroids probably do not cause important adverse effects.

PMID: 28306710 [PubMed - in process]

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