Hunting Down the HIV-1 Reservoir: A Starring Role for Antibodies?

Publication date: 18 April 2017
Source:Immunity, Volume 46, Issue 4
Author(s): Hugo Mouquet
The persistence of viruses "hidden" in a reservoir of latently infected CD4⁺ T cells under antiretroviral therapy is the major obstacle to an HIV-1 cure. Recently published in Nature, two seminal studies from Descours et al. (2017) and Nishimura et al. (2017) bring hope for tracking and possibly eradicating the HIV-1 reservoir.

Teaser

The persistence of viruses "hidden" in a reservoir of latently infected CD4 T cells under antiretroviral therapy is the major obstacle inhibiting an HIV-1 cure. Recently published in Nature, two seminal studies from Descours et al. (2017) and Nishimura et al. (2017) bring hope for tracking and possibly eradicating the HIV-1 reservoir.


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