Malignant transformation of oral lichen planus and oral lichenoid lesions: A meta-analysis of 20095 patient data

Oral Lichen Planus (OLP) is an oral subtype of Lichen Planus, affecting 1–4% of the worldwide population with a higher frequency in middle aged and elderly women [1]. It is a chronic inflammatory disease, characterized by a T-cell mediated response against epithelial basal cells, leading to basal cell degeneration and subepithelial band like infiltration by T-lymphocytes [2,3]. Clinically, there are six different subtypes, classified into two groups: Non-erosive-atrophic forms [including reticular, papular and plaque like] and erosive-atrophic forms [including atrophic (erythematous), erosive (ulcerative) and bullous] [4].

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