Multidisciplinary management of head and neck cancer: First expert consensus using Delphi methodology from the Spanish Society for Head and Neck Cancer (part 1)

HNSCC is the fifth most common malignancy worldwide and the eighth most common cause of cancer-related mortality [1,2]. Tobacco and alcohol abuse are the main risk factors, but in the past few years HPV infection has emerged as a new risk factor for a substantial percentage of HNSCC-especially in oropharyngeal cancer (OPC) [3]. Only one third of the patients present with early stage disease, while most of them will have locally advanced (LA) disease by the time of diagnosis [4]. In these patients, 5-year survival has remained invariable in the last decades [5].

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