Outcome of Hematopoietic Cell Transplantation for DNA-Double Strand Breakage Repair Disorders

Hematopoietic cell transplant cures DNA breakage-repair disorders. Cernunnos-XLF deficiency, LIG4 and Nijmegen breakage syndrome patients receiving alkylator or radiotherapy pre-conditioning have worse survival than those receiving reduced intensity conditioning.

http://ift.tt/2oSRep9