Protective effect of Hua Tan Qu Shi decoction against liver injury in rats with nonalcoholic fatty liver disease

Publication date: July 2017
Source:Biomedicine & Pharmacotherapy, Volume 91
Author(s): Shi Peng Zhao, Zhi Sheng Wu, Yu Chen, Xue Liang, Lei Bao, Pin Li, Ran Ran Sun, Yan Ling Wu, Ling Ru Li, Qi Wang
BackgroundNonalcoholic fatty liver disease (NAFLD), is currently a worldwide health problem. None of the existing treatment medications had got a satisfactory effect. Hua Tan Qu Shi (HTQS) decoction is a Chinese herbal formula, which has been used clinically to treat NAFLD for years. However, the underlying mechanisms are still unclear.MethodsHigh-fat diet (HFD) induced non-alcoholic fatty liver disease rats treated with or without HTQS decoction by gavage for 10 weeks and examined by serology, 24-h albuminuria, histology, immunohistochemistry, and molecular analyses.



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