Acute and painful exacerbation of RLS and PLM induced by opioid interaction - withdrawal syndrome

An 87-year-old, non-demented man with long-standing history of restless legs syndrome (RLS) was admitted to the emergency unit with acute pain and motor restlessness, as well as intense periodic limb movements (PLMs) occurring approximately every 20 seconds, involving the whole body(eg, both legs, arms, and the trunk).

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