Dataset on characterization of hemin-azide derivative and DNA oligonucleotide-hemin conjugate

Publication date: August 2017
Source:Data in Brief, Volume 13
Author(s): J. Kosman, A. Stanislawska, A. Gluszynska, B. Juskowiak
In this article newly synthesized azide derivative of hemin and DNA-hemin conjugate are characterized. Hemin-azide was purified using HPLC and characterized using elemental analysis, IR and NMR. The DNA-hemin conjugate was obtained via click chemistry [1] and click reaction was carried out using traditional Cu-catalyzed and Cu-free approaches. The final product was successfully obtained using Cu-free cycloaddition. The identity of product was confirmed using Maldi TOF spectrometry. Obtained hemin-DNA conjugate exhibited peroxidase-like activity.



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