Endoscopic endonasal resection of a mixedlesion of gangliocytoma and non-functioning pituitary adenoma.

Related Articles

Endoscopic endonasal resection of a mixedlesion of gangliocytoma and non-functioning pituitary adenoma.

World Neurosurg. 2017 May 19;:

Authors: Heng LJ, Jia D, Gong L, Zhang W, Ma J, Qu Y

Abstract
BACKGROUND: The coexistence of a gangliocytoma and a pituitary adenoma is a rare event, which has only been studied in case reports previously. The knowledge of its diagnosis and treatment is extremely limited.
CASE DESCRIPTION: We present a rare case of intrasellar-suprasellar gangliocytoma and non-functioning pituitary adenoma. The lesion was preoperatively diagnosed as a pituitary adenoma and resected using the extended endoscopic endonasal approach. We could clearly observe two different textures inside the tumor. The main body of the tumor tissue was tough and fibrous with distinct lobular nodules distributed within it. To the best of our knowledge, this is the first report of distinct compartments with heterogeneous consistencies in a mixed sellar gangliocytoma-adenoma.
CONCLUSIONS: Our finding of the heterogeneous texture in the lesion of gangliocytoma associated with pituitary adenoma may help uncover the pathogenesis of this rare disorder, which also supports the examination of intraoperative frozen sections to aid in diagnosis. We recommend maximized safe resection as a surgical strategy for the coexistent lesion of gangliocytoma and pituitary adenoma.

PMID: 28532920 [PubMed - as supplied by publisher]

http://ift.tt/2qVoz4e