Unfolding the Folding Problem of the Cerebral Cortex: Movin’ and Groovin’

Publication date: 22 May 2017
Source:Developmental Cell, Volume 41, Issue 4
Author(s): Yasuhiro Itoh, Alexandros Poulopoulos, Jeffrey D. Macklis
The development of reproducible folding in the gyrencephalic cerebral cortex is a topic of great interest to neuroscientists. In a recent paper in Cell, del Toro et al. (2017) show that changing the adhesive properties of neurons in the normally lissencephalic mouse cortex leads to the formation of stereotyped folding.

Teaser

The development of reproducible folding in the gyrencephalic cerebral cortex is a topic of great interest to neuroscientists. In a recent paper in Cell, del Toro et al. (2017) show that changing the adhesive properties of neurons in the normally lissencephalic mouse cortex leads to the formation of stereotyped folding.


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