Can the combined administration of labelled fluoro-2 deoxy D glucose and insulin or chrome increase the diagnostic sensitivity of Positron Emission Tomography?

Publication date: Available online 9 June 2017
Source:Medical Hypotheses
Author(s): Suleyman Aydin
In this letter to editor I hypothesize that administeringinsulinorchromealong with fluoro-2 deoxy D-glucose (FDG) to enhance its uptake in malignant lesions that are known to have low levels of tumor glycolysis, and therefore, improve the sensitivity of PET imaging in this setting. The logic behind this idea stems from the known fact that there is substantialincreasein uptake of D-glucose following administration ofinsülin/ chromein many tissues, and as such, the same pattern would apply to FDG.



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