Controversies in Postoperative Irradiation of Oropharyngeal Cancer After Transoral Surgery.

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Controversies in Postoperative Irradiation of Oropharyngeal Cancer After Transoral Surgery.

Surg Oncol Clin N Am. 2017 Jul;26(3):357-370

Authors: Yom SS, Mallen-St Clair J, Ha PK

Abstract
Transoral surgery (TOS) is a novel technology whose adoption is expanding in the United States and other countries. TOS offers the possibility of a minimally invasive surgical approach to head and neck cancers. Its most frequent application has been in oropharyngeal cancers (OPC), of which most are associated with human papillomavirus (HPV). For HPV-associated OPC, where high response and survival rates are expected, deintensification of standard therapy is a major area of clinical research. In HPV-OPC, traditional pathologic risk factors indicating a need for adjuvant radiation or chemoradiation may not apply as strongly.

PMID: 28576176 [PubMed - in process]

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