Evidence for altered levels of Immunoglobulin D in the nasal airway mucosa of patients with chronic rhinosinusitis

Soluble IgD levels and IgD+CD19+CD38bright plasmablasts were significantly increased in nasal airway mucosa from patients with CRSsNP. Local factors including IL-2 levels and presence of pathogenic bacteria may enhance IgD production in nasal airway mucosa.

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