Management of a multiple endocrine neoplasia type 1 during pregnancy: A case report and review of the literature.

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Management of a multiple endocrine neoplasia type 1 during pregnancy: A case report and review of the literature.

J Exp Ther Oncol. 2016 Jul;11(3):217-220

Authors: Daglar HK, Kirbas A, Biberoglu E, Laleli B, Danisman N

Abstract
Multiple Endocrine Neoplasia Type 1 (MEN1) or Wermer's syndrome is a rare hereditary endocrine syndrome with high penetrance caused by mutations in MEN1 tumor suppressor gene. MEN1 is characterized by hyperplasia or tumoral enlargement in a number of endocrine organs (parathyroid glands, pancreas, pituitary gland, adrenal gland) and it could be hormonally active or inactive. MEN1 is a significant cause of morbidity due to hormone secretion and mass effect. Since it is a rare condition, there are no guidelines with respect to the follow-up of pregnant women with MEN1. Herein, we aimed to present the diagnosis and gestational follow-up of a 29-year-old pregnant with MEN1 syndrome.

PMID: 28471129 [PubMed - indexed for MEDLINE]

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