Decoding the signaling pathway initiating cellular migration in cancer metastasis

The most common reason for mortality in cancer is Metastasis. The spread of cancer cells to vital structures leading to its dysfunction culminates in either severe morbidity or mortality. Researchers have formulated multiple therapeutic agents to combat the rapid proliferation of cancer cells. Preventing the cellular proliferation is just half the battle, as highly invasive tumors have a tendency to have low proliferative but high invasive properties. In such cases, although the anti-proliferative agent's blocks/inhibits the primary tumor growth, it is largely ineffective in preventing the rise of secondary tumors.

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