Genetic and epigenetic regulation of YKL-40 in childhood

Circulating YKL-40 and variation in its encoding gene CHI3L1 have been associated with asthma. We found that methylation levels at CHI3L1 CpG sites partly mediated CHI3L1 genetic effects on circulating YKL-40, although they were not associated with childhood asthma.

http://ift.tt/2gRbtnl