Impact of oral gut decontamination on staphylococcus aureus colonization in patients undergoing allogeneic hematopoietic stem cell transplantation.

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Impact of oral gut decontamination on staphylococcus aureus colonization in patients undergoing allogeneic hematopoietic stem cell transplantation.

Int J Antimicrob Agents. 2017 Aug 07;:

Authors: Wilk CM, Weber I, Seidl K, Rachmühl C, Holzmann-Bürgel A, Müller AMS, Kuster SP, Schanz U, Zinkernagel AS

Abstract
Recipients of allogeneic hematopoietic stem cell transplantation (allo-HSCT) are severely immunocompromised and at increased risk for infections. In this prospective, observational, single-center study including 110 HSCT-recipients, the S. aureus colonization rate was reduced from 12% to 0% (p<0.001) following peri-transplant oral gut decontamination. No invasive S. aureus infections were observed.

PMID: 28797807 [PubMed - as supplied by publisher]

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