Acylglycerol Kinase: Mitochondrial Protein Transport Meets Lipid Biosynthesis

Publication date: Available online 31 August 2017
Source:Trends in Cell Biology
Author(s): Christoph U. Mårtensson, Thomas Becker
The carrier translocase (TIM22 complex) inserts hydrophobic proteins into the mitochondrial inner membrane. Recently, the acylglycerol kinase (AGK) mutated in Sengers syndrome was identified as a novel subunit of the human TIM22 complex. This finding reveals an exciting link between mitochondrial protein and lipid biogenesis.



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