Advancing toward a molecular characterization of polymorphous low grade adenocarcinoma

Polymorphous low-grade adenocarcinoma (PLGA) is the second most common intraoral salivary gland malignancy; it affects predominantly the minor salivary glands of the palate, but has been reported to occur in the major salivary glands as well as extra palatal sites [1–3]. Despite the tendency for locally infiltrative growth, and the notable amount of locoregional recurrences, PLGA is characterized by an indolent clinical course with low risk of distant metastasis and good long-term prognosis [1,3].

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