Intraindividual homogeneity of 18F-FDG PET/CT parameters in HPV-positive OPSCC

Head and neck squamous cell carcinoma (HNSCC) is one of the most prevalent malignancies and the 7th most common cause of cancer-induced mortality worldwide [1]. While incidence rates for cancer of the hypopharynx and larynx are decreasing, a significant increase in cancer of the oropharynx (OPSCC) has been observed [2]. Because of differences in risk factors, clinical course and outcome, HPV-positive tumours are considered to be a distinct entity and therefore have recently been added to the TNM/AJCC Cancer Staging Manual [3–7].

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