Visualizing Nuclear RNA Editing

Publication date: Available online 28 September 2017
Source:Trends in Biochemical Sciences
Author(s): Hodaya Hochberg, Yaron Shav-Tal
RNA editing results in the site-specific conversion of adenosine to inosine in mRNAs. Genomics has revealed millions of editing sites in metazoans, but examining the spatial aspects of editing in cells has been challenging. A new method, inosineFISH (inoFISH), provides the ability to detect edited and unedited mRNAs within intact cells.



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