Vitamin D and the paraventricular nucleus: relevance for Type 2 Diabetes

Publication date: Available online 6 October 2017
Source:The Journal of Steroid Biochemistry and Molecular Biology
Author(s): Keisha Harrison, Stephanie Sisley
Vitamin D deficiency is linked to type 2 diabetes and we recently showed this may be through action of vitamin D in the paraventricular nuclei (PVN) in the hypothalamus of the brain. This review focuses on the known roles of the PVN in glucose control and how previously discovered actions of vitamin D in other tissues may translate to action in the PVN. Specifically, we focus on the role of insulin and inflammation in the hypothalamus and how these may be modified through vitamin D action.



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