P428 The empty nose syndrome (ENS): a diagnostic and therapeutic challenge for the allergist-immunologist

ENS is a rare rhinological disorder occurring months to years after sinonasal surgery, with symptoms of paradoxical nasal obstruction, nasal dryness, crusting, and dyspnea. Little is known of its pathogenesis, although anatomical changes leading to disruption of mucosal cooling, and disordered neurosensory mechanisms are strongly implicated. Medical therapies include mucosal humidification, irrigations, emollients, and surgical therapy with turbinate reconstruction reserved for refractory cases.

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