Sputum cell interleukin-1 receptor expression level is a marker of airway neutrophilia and airflow obstruction in asthma

Though expression levels of airway type-1, type-2 and type-17 markers are correlated, PLS analysis identifies the IL-1 receptor as predictive of neutrophilic asthma. The IL-1 pathway may be a potential therapeutic target in neutrophilic asthma.

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