Sweet! Helicobacter Sugar Calms Intestinal Macrophages

Publication date: 13 December 2017
Source:Cell Host & Microbe, Volume 22, Issue 6
Author(s): Calum C. Bain, Marika C. Kullberg
In the absence of IL-10, Helicobacter hepaticus (Hh) induces colitis. In this issue of Cell Host & Microbe, Danne et al. (2017) report that Hh produces a polysaccharide that induces an anti-inflammatory response in macrophages, providing a potential clue as to why this bacterium is normally tolerated by the immune system.

Teaser

In the absence of IL-10, Helicobacter hepaticus (Hh) induces colitis. In this issue of Cell Host & Microbe, Danne et al. (2017) report that Hh produces a polysaccharide that induces an anti-inflammatory response in macrophages, providing a potential clue as to why this bacterium is normally tolerated by the immune system.


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