The inhibitor of apoptosis protein livin is upregulated in psoriasis vulgaris

Psoriasis vulgaris (PV) is widely considered as a chronic inflammatory skin disease which is characterized hyperplasia with incomplete differentiation and decreased apoptosis of epidermal keratinocytes(1). The patients with PV suffer severe physical and psychological discomfort, and often have decreased life quality. However, traditional treatments of PV cannot meet the needs of patients(2). So it is crucial and urgent to explore the underlying molecular mechanism of PV and develop new target therapy to PV.

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