Magnesium as an Alternative or Adjunct to Opioids for Migraine and Chronic Pain: A Review of the Clinical Effectiveness and Guidelines [Internet].

Migraine and chronic pain are common disorders and can result in considerable disability. According to the World Health Organization, migraine is ranked 19th with respect to health disorders causing life lived with disability. The lifetime prevalence of migraine in Canada has been estimated to be 24% in women and 9% in men. Chronic pain is defined as pain that persists for greater than three months. Chronic pain is associated with a variety of disorders such as chronic low back pain, chronic complex regional pain syndrome (CPRS), fibromyalgia and neuropathy. Estimates of the prevalence of chronic pain in Canada vary between 16% and 40%. The variability may be due to differences in the definitions used for chronic pain, sample populations surveyed, and the survey methodologies.

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