Clinical research with high risk patient populations is complex due to economic burdens, lack of transportation, etc.1, 2; therefore, it is critical to conduct pilot studies prior to entering into a full scale study. Pilot studies can confirm the design and operational processes for a study3 and increase the likelihood of a successful clinical trial by identifying problems that may occur in the methods.4, 5 Thus, we conducted a pilot study to identify issues in a research trial with low-income, publically insured, minority adolescents.
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