Concordance with anaphylaxis care guidelines and the impact on healthcare resource utilization in the USA

For patients who have experienced anaphylaxis, United States (US) guidelines recommend first-line therapy with epinephrine to prevent fatalities, as well as prescription of an epinephrine auto-injector (EAI), referral to an allergist/immunologist, and training to identify and avoid the responsible allergen.1–3 However, adherence to these guidelines is low4–6 and generally, patients face increased healthcare resource utilization (HCRU) and associated costs.4

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