The Agency for Healthcare Research and Quality (AHRQ) Evidence-based Practice Center (EPC) program engages patients, caregivers, and patient advocates in several steps of a systematic review to ensure that their perspective is included. One place where patients, caregivers, and patient advocates are used extensively is as Key Informants (KIs). An EPC utilizes a panel of patients/patient advocates, researchers, and clinicians in the topic refinement phase of a project to ensure the EPC understands the issues important to these stakeholders. The EPCs use this feedback to refine the topic area's analytic framework; its Patient population, Interventions, Comparators, Outcomes, Timing, and Settings (PICOTS); and the Key Questions that when answered will contribute important information to the health care system.
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