Staphylococcus aureus enhances the tight junction barrier integrity in healthy nasal tissue, but not in nasal polyps.

Staphylococcus aureus enhances the tight junction barrier integrity in healthy nasal tissue, but not in nasal polyps.

J Allergy Clin Immunol. 2018 Mar 05;:

Authors: Altunbulakli C, Costa R, Lan F, Zhang N, Akdis M, Bachert C, Akdis CA

Abstract
Staphylococcus aureus infection increases the expression of the tight junctions (TJs) in healthy nasal tissue; while nasal polyps show decreased TJ expression at baseline and are unable to upregulate TJs to strengthen the epithelial barrier.

PMID: 29518417 [PubMed - as supplied by publisher]

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