Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
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alsfakia@gmail.com

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Σάββατο 14 Απριλίου 2018

[Chemoradiotherapy, the Standard Treatment at Present].

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[Chemoradiotherapy, the Standard Treatment at Present].

Gan To Kagaku Ryoho. 2018 Mar;45(3):412-415

Authors: Zenda S

Abstract
Chemotherapy concurrent with radiotherapy has been widely used in clinical practice because the additional benefit on radiotherapy alone had shown. Head and neck cancer: CDDP concurrent with radiotherapy has been a standard treatment for 15years both in definitive setting and postoperative setting. Esophageal cancer: 5-FU/CDDP is the best partner for radiotherapy and appropriate radiation dose has been discussed. Anal cancer: Radical concurrent chemoradiotherapy with 5-FU and mitomycin C(MMC)remains the standard of care for squamous cell carcinoma of the anus. Recent radiotherapy techniques can realize decreasing radiation doses to the organs at risk and ensuring a shorter overall treatment time without the need for treatment breaks. In medical oncology field, some molecular targeting agents containing regimens had been standard treatments instead of conventional therapies from 2000. However, there are a few regimens which can change the standard in combination with radiotherapy at this point. We hope new regimens with radiotherapy will emerge and replace the conventional standard in near future.

PMID: 29650894 [PubMed - in process]



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