Detection of adamantane-sensitive influenza A(H3N2) viruses in Australia, 2017: a cause for hope?

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Detection of adamantane-sensitive influenza A(H3N2) viruses in Australia, 2017: a cause for hope?

Euro Surveill. 2017 Nov;22(47):

Authors: Hurt A, Komadina N, Deng YM, Kaye M, Sullivan S, Subbarao K, Barr I

Abstract
For over a decade virtually all A(H3N2) influenza viruses have been resistant to the adamantane class of antivirals. However, during the 2017 influenza season in Australia, 15/461 (3.3%) adamantane-sensitive A(H3N2) viruses encoding serine at residue 31 of the M2 protein were detected, more than the total number identified globally during the last 6 years. A return to wide circulation of adamantane-sensitive A(H3N2) viruses would revive the option of using these drugs for treatment and prophylaxis.

PMID: 29183552 [PubMed - indexed for MEDLINE]

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