Fatty Acid Oxidation in Cell Fate Determination

Publication date: Available online 4 May 2018
Source:Trends in Biochemical Sciences
Author(s): Jianhua Xiong
Mitochondrial fatty acid β-oxidation (FAO) is a major catabolic process that degrades long-chain fatty acids. Recent reports reveal a broad role for FAO in cell fate control in endothelial cells, immune cells, and cancer cells. Concurrently, unique molecular pathways influenced by FAO have been identified that alter cell fate decisions.



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