The Challenges of Preventing Food Allergy: lessons learned from LEAP and EAT

Driven by both the continuing rise in food allergy prevalence1, 2 and the lack of an effective cure, the last decade has seen an increase in clinical trials investigating the prevention of food allergy. Earlier wisdom, predominantly derived from the findings of observational studies, considered that allergy prevention was best achieved through allergen avoidance.3, 4 After testing under randomised controlled trial (RCT) conditions, allergen avoidance has not been deemed a suitable means of preventing food allergy.

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